HOMECNS Micro Animation:Micro

CNS Macro Animation:Micro

Myelin destruction (secondary change)

Primary destruction of the myelin sheath is called demyelination in the narrow sense and refers to demyelinating diseases such as multiple sclerosis and leukodystrophy. Because the myelin sheath is primarily destroyed, the axons are relatively preserved. In the broader sense, on the other hand, secondary myelin sheath destruction may also be called demyelination but it is not demyelination in a true sence.