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Cellular Pathology


Isomorphic gliosis

Holzer stain

  • In the cerebellar white matter of olivo-ponto-cerebellar atrophy, fibrous astrocytes grow and form gliosis with the destruction of axons and myelin sheaths. A bundle of fibers (arrows) stained purple is the gliosis part. This pattern of gliosis is called isomorphic gliosis.